[Intensive therapy in high fever in young children at the prehospital stage]

Area of Science:

• Pediatrics
• Neurology
• Pharmacology

Background:

• High fever in children can lead to severe complications like encephalopathy and epileptic syndrome.
• Circulation centralization is a critical indicator of fever severity in pediatric patients.
• Understanding clinical signs of circulation centralization is crucial for effective fever management.

Purpose of the Study:

• To determine the efficacy of droperidol in treating severe high fever with encephalopathy and epileptic syndrome in children.
• To identify key clinical signs indicative of circulation centralization in pediatric febrile illnesses.
• To assess factors influencing the prognosis of high fever in children.

Main Methods:

• Clinical observation of pediatric patients experiencing high fever.
• Assessment of neurological status, including consciousness and presence of seizures.
• Monitoring of vital signs such as blood pressure and temperature differentials.
• Evaluation of skin perfusion and extremity temperature as indicators of circulation centralization.

Main Results:

• Droperidol treatment is indicated for severe cases of high fever complicated by encephalopathy and epileptic syndrome.
• Clinical signs of severe circulation centralization include marble skin, disturbed consciousness, elevated blood pressure, and a significant rectal-axillary temperature difference.
• Children without concomitant diseases and with moderately expressed signs of circulation centralization (pale skin, cool extremities) had a more favorable fever course.

Conclusions:

• Droperidol is a viable therapeutic option for severe pediatric febrile conditions involving neurological compromise.
• Early recognition of specific clinical signs of circulation centralization aids in risk stratification and treatment decisions.
• Prognosis is improved in children with uncomplicated high fever and less severe circulatory disturbances.