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Injection sclerotherapy for esophageal varices
1Department of Surgery, North Karelian Central Hospital, Joensuu, Finland.
Summary
Endoscopic injection sclerotherapy effectively obliterates bleeding esophageal varices in 89% of patients. This safe treatment for esophageal varices requires multiple sessions but improves survival rates.
Area of Science:
- Gastroenterology
- Endoscopy
- Interventional Procedures
Background:
- Esophageal varices are a serious complication of portal hypertension.
- Bleeding from esophageal varices carries a high mortality rate.
- Endoscopic sclerotherapy is a primary treatment modality.
Purpose of the Study:
- To evaluate the efficacy and safety of endoscopic injection sclerotherapy for bleeding esophageal varices.
- To determine the obliteration rates and required sessions for variceal eradication.
- To assess patient survival following sclerotherapy.
Main Methods:
- Thirty-five patients with bleeding esophageal varices underwent repeated endoscopic injection sclerotherapy.
- 5% ethanolamine oleate was injected submucosally or intravariceally.
- Varices were injected with 14 +/- 4.2 ml per session.
Main Results:
- Variceal obliteration was achieved in 89% of patients (31 out of 35).
- An average of 3.3 +/- 2.4 sessions were needed for eradication.
- Complications included mild fever, one case of mediastinitis, and two cases of esophageal stricture.
Conclusions:
- Endoscopic injection sclerotherapy is an effective and safe treatment for bleeding esophageal varices.
- The procedure leads to high obliteration rates and improved survival.
- Sclerotherapy offers a viable therapeutic option for managing this critical condition.