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Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation
Published on: April 14, 2016
A review of postgastrectomy bone disease
1Department of Surgery, University College and Middlesex School of Medicine, London, UK.
Journal of Gastroenterology and Hepatology
|November 1, 1992
Summary
Postgastrectomy bone disease, including osteomalacia and osteoporosis, can occur after surgery. Early screening with alkaline phosphatase and bone density assessments is crucial for managing these metabolic bone disorders.
Area of Science:
- Endocrinology
- Metabolic Bone Disease
Background:
- Postgastrectomy bone disease encompasses metabolic bone disorders like osteomalacia and osteoporosis following gastrectomy.
- While gastrectomy rates have declined, these bone conditions persist and can be overlooked.
Purpose of the Study:
- To review screening methods for postgastrectomy bone disease.
- To discuss the current prevention and treatment strategies for associated osteomalacia and osteoporosis.
Main Methods:
- Review of literature on postgastrectomy bone disease.
- Analysis of screening procedures including plasma alkaline phosphatase and bone mineral density assessment.
Main Results:
- Plasma alkaline phosphatase levels aid in screening for osteomalacia, treatable with calcium and vitamin D.
- Osteoporosis exceeding normal aging is a significant issue with currently unsatisfactory prevention and treatment.
Conclusions:
- Osteomalacia and osteoporosis are key components of postgastrectomy bone disease.
- Excluding osteomalacia is essential before diagnosing osteoporosis; effective osteoporosis management remains a challenge.
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