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Translocation t(12;22)(q13;q13) is a nonrandom rearrangement in clear cell sarcoma
B R Reeves1, C D Fletcher, B A Gusterson
1Section of Pathology, Institute of Cancer Research, Sutton, Surrey, United Kingdom.
Cancer Genetics and Cytogenetics
|December 1, 1992
Abstract:
Cytogenetic analyses of tumor cells from a case of clear cell sarcoma revealed a translocation between chromosomes 12 and 22 that was similar to the rearrangement described recently in three other cases. It is suggested that the translocation may be important in the pathogenesis of this rare tumor.