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Deletion (7)(p11p15) in a patient with Philadelphia-positive chronic myelogenous leukemia
J L Carrasco Juan1, A Otero Gómez, J L García Miranda
1Cytogenetics Service, Faculty of Medicine, University of La Laguna, Tenerife, Canary Islands, Spain.
Cancer Genetics and Cytogenetics
|December 1, 1992
Abstract:
We report a case of chronic myelogenous leukemia (CML) with a Philadelphia (Ph) chromosome. During the transformation phase of the disease, a del(7)(p11p15) and a +Ph were identified as additional chromosomal anomalies. We believe that loss of the segment 7p11-->p15 may play an important role in the progression of the disease.