[Significance of immunologic reactions on the surface of intraocular lenses]

The authors summarize their experience assembled during specular examinations of immunological processes on the surface of the intraocular lens. They describe the incidence of significant components of the immunological reaction--of "large cells", "fibroblast-like cells", round elements, fibrous and acellular membranes on the surface of the intraocular lens. The "large cells" are considered the most important components of the reaction from the clinical aspects. Their incidence depends most frequently on a change in the position of the intraocular lens and non-adherence to therapy in the early postoperative stage. The authors present findings assembled in patients with late changes of the position and formation of synechiae and subluxation, most probably traumatic, and occur in patients who did not respect local corticoid treatment in the early postoperative period. A similar character of the specular finding indicates uniformity of the non-specific reaction which is potentiated by interference with the haemotoocular barrier for various reasons.