Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Nerve-sparing radical hysterectomy: a pilot study.

Francesco Raspagliesi1, Antonino Ditto, Shigeki Kusamura

  • 1Department of Gynecologic Oncology, National Cancer Institute, Milan, Italy.

Tumori
|February 12, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The TRUST trial in ovarian cancer: a missed opportunity or a turning point? The position of the Italian MITO group.

Frontiers in oncology·2026
Same author

Revisiting the Concept of Nerve-Sparing Radical Hysterectomy: A Proof-of-Concept Prospective Study From a Cervical Cancer Cohort.

Annals of surgical oncology·2026
Same author

Immunotherapy with anti-PD-1 or PD-L1 in advanced ovarian cancer: A meta-analysis of randomized trials.

Cancer treatment reviews·2026
Same author

Effectiveness of azacytidine for poly ADP-ribose polymerase inhibitor-induced myelodysplastic syndrome in ovarian cancer patient: a twofold triumph.

Journal of chemotherapy (Florence, Italy)·2026
Same author

Fertility-sparing vs hysterectomy for uterine STUMP: A pragmatic clinical study.

European journal of cancer (Oxford, England : 1990)·2026
Same author

ASO Author Reflections: Probe-Based Confocal Laser Endomicroscopy for Intraoperative Tissue Assessment in Gynecologic Oncology.

Annals of surgical oncology·2026

This study introduces a nerve-sparing radical hysterectomy technique for cervical cancer, showing it

Area of Science:

  • Gynecologic Oncology
  • Surgical Innovation
  • Urogynecology

Background:

  • Nerve-sparing radical hysterectomy is gaining traction for cervical cancer treatment, aiming to minimize patient morbidity.
  • Understanding the autonomic nervous system's surgical anatomy is crucial for preserving nerve function during hysterectomy.
  • Bladder dysfunction is a significant concern following radical hysterectomy, impacting patient quality of life.

Purpose of the Study:

  • To present an alternative nerve-sparing radical Piver III hysterectomy technique utilizing CUSA, focusing on uterosacral and cardinal ligaments.
  • To assess the feasibility and safety of this novel nerve-sparing surgical approach.
  • To evaluate the early incidence of postoperative bladder dysfunction in patients undergoing this procedure.

Main Methods:

Related Experiment Videos

  • Twelve patients with local-regional advanced cervical cancer underwent nerve-sparing radical hysterectomy with extended pelvic lymphadenectomy.
  • The CUSA (Cavitational Ultrasonic Surgical Aspirator) was employed, with meticulous attention to preserving autonomic nerve structures.
  • Surgical anatomy of the pelvic autonomic nervous system was described, and postoperative bladder function was monitored.

Main Results:

  • The mean operating time was 217 minutes, with an average blood loss of 437 cc and hospitalization of 9 days.
  • Two patients (17%) experienced temporary bladder dysfunction requiring self-catheterism; one recovered spontaneous voiding by the first follow-up.
  • The technique was feasible, with promising initial results in preventing severe bladder dysfunction.

Conclusions:

  • The described nerve-sparing radical hysterectomy technique using CUSA offers a viable option to reduce surgical morbidity.
  • This approach demonstrates feasibility and potential benefits in preserving bladder function post-surgery.
  • Further research, including neuroanatomical studies and prospective trials, is warranted to validate these findings.