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Updated: Aug 27, 2026

Development of a Backbone Cyclic Peptide Library as Potential Antiparasitic Therapeutics Using Microwave Irradiation
Published on: January 26, 2016
Microwaves in drug discovery and multi-step synthesis
François-René Alexandre1, Lisianne Domon, Stéphane Frère
1LGPC UPRES EA3169, Groupe de Chimie Organique UFR Sciences Fondamentales et Sciences pour l'Ingénieur, Université de la Rochelle, Bâtiment Marie-Curie, La Rochelle Cedex 1, France.
Abstract:
The interest of microwaves in drug discovery and multi-step synthesis is exposed with the aim of describing our strategy. These studies are connected with our work on the synthesis of original heterocyclic compounds with potential pharmaceutical value. Reactions in the presence of solvent and solvent-free synthesis can be realised under a variety of conditions; for some of these selected results are given, and where available, results from comparison with the same solvent-free conditions but with classical heating are given.
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