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Use of IGIV in the treatment of immune-mediated dermatologic disorders

Erwin W Gelfand1

  • 1Division of Cell Biology, Department of Pediatrics, National Jewish Medical and Research Center, Denver, Colorado 80206, USA. gelfande@njc.org

The Journal of Investigative Dermatology. Symposium Proceedings
|February 12, 2004
PubMed

Immunoglobulin (Ultravenous, IGIV) is now used in a variety of immune-mediated diseases. Its presumed mechanism of action involves both anti-inflammatory and immunomodulatory activities. A number of dermatologic conditions are believed to be immune mediated and in these disorders, IGIV has shown benefit in reducing symptoms and the need for cortecosteroids or cytotaxic drugs. In many of these diseases, the initial benefits seen in open-labeled trials must be confirmed in controlled clinical trials.

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