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WebVar: A resource for the rapid estimation of relative site variability from multiple sequence alignments
Flavio Mignone1, David S Horner, Graziano Pesole
1Dipartimento di Scienze Biomolecolari e Biotecnologie, Università di Milano, 20113 Milano, Italy.
Bioinformatics (Oxford, England)
|February 12, 2004
Summary
WebVar offers estimates of relative site variability from protein and nucleic acid sequence alignments. This tool aids in phylogenetic analysis with graphical and textual representations.
Area of Science:
- Bioinformatics
- Computational Biology
- Evolutionary Biology
Background:
- WebVar is an accessible online resource.
- The server is available at http://www.pesolelab.it/Tools/WebVar.html.
Purpose of the Study:
- To provide estimates of relative site variability.
- To support phylogenetic analysis through data visualization.
Main Methods:
- Analysis of multiple sequence alignments of homologous protein and nucleic acid sequences.
- Generation of graphical and textual representations of variability estimates.
Main Results:
- Provides quantitative measures of site variability.
- Offers diverse data visualizations for interpretation.
Conclusions:
- WebVar is a valuable tool for researchers conducting phylogenetic analyses.
- Facilitates the understanding of sequence evolution and variation.