OVCA1: emerging as a bona fide tumor suppressor

Epigenetic and oncogenic inhibitors converge to drive a metabolic catastrophe in castration-resistant prostate cancer.

The Journal of clinical investigation·2026

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites.

eLife·2026

Addressing the specific roles of histone modifications in transcriptional repression.

Nature communications·2025

Functional dissection of H3K4 methyltransferases reveals distinct catalytic and non-catalytic roles in C. elegans development.

Development (Cambridge, England)·2025

A needed nomenclature for nucleosomes.

Molecular cell·2025

Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation.

Molecular cell·2025

mTOR inactivation governs adaptive survival to ribosome biogenesis deficiency.

Genes & development·2026

Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities.

Genes & development·2026

A conserved Notch-Meis1-Pbx cascade specifies secretory progenitors into spatially diverse intestinal best4 + cells.

Genes & development·2026

RBM39 modulates UPR signaling through alternative splicing of IRE1α/ERN1.

Genes & development·2026

Nuclear type I myosins actively support nucleolar and nuclear structure and function.

Genes & development·2026

Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity.

Genes & development·2026

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Letter to "NR1D2 Knockdown Alleviates Myocardial Infarction Through Nrf2 Signaling Pathway Activation".

Cardiovascular drugs and therapy·2026

The Protective Effect of Astragalus Polysaccharides Against Cisplatin‑Induced Pulmonary Epithelial Cell Injury: An Integrated Network Toxicology and In Vitro Validation.

Cell biochemistry and biophysics·2026

H2AFY2 suppresses exhaustion and enhances antitumor activity of CAR-T cells through transcriptional and epigenetic modifications.

Cancer immunology research·2026

ERK1/2 Inhibitor Ulixertinib in Pan-cancer Patients with BRAF Fusions or Non-V600E/K Mutations: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1L.

Clinical cancer research : an official journal of the American Association for Cancer Research·2026

Inhibiting Ribosomal RNA Synthesis in C. elegans Protects Against Reductive Stress During de novo Fatty Acid Synthesis Deficiency.

Genetics·2026

Related Experiment Videos

OVCA1: emerging as a bona fide tumor suppressor

Related Concept Videos

Epigenetic and oncogenic inhibitors converge to drive a metabolic catastrophe in castration-resistant prostate cancer.

Acetylation of H3K115 is associated with fragile nucleosomes at CpG island promoters and active regulatory sites.

Addressing the specific roles of histone modifications in transcriptional repression.

Functional dissection of H3K4 methyltransferases reveals distinct catalytic and non-catalytic roles in C. elegans development.

A needed nomenclature for nucleosomes.

Non-canonical PRC1.1 licenses transcriptional response to enable Treg plasticity in immune adaptation.

mTOR inactivation governs adaptive survival to ribosome biogenesis deficiency.

Human PIF1 clears secondary DNA structures by coupled DNA unwinding and rewinding activities.

A conserved Notch-Meis1-Pbx cascade specifies secretory progenitors into spatially diverse intestinal best4 + cells.

RBM39 modulates UPR signaling through alternative splicing of IRE1α/ERN1.

Nuclear type I myosins actively support nucleolar and nuclear structure and function.

Neuronal expression of bromodomain proteins alters neuronal health and peripheral protein homeostasis to promote longevity.

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain.

Letter to "NR1D2 Knockdown Alleviates Myocardial Infarction Through Nrf2 Signaling Pathway Activation".

The Protective Effect of Astragalus Polysaccharides Against Cisplatin‑Induced Pulmonary Epithelial Cell Injury: An Integrated Network Toxicology and In Vitro Validation.

H2AFY2 suppresses exhaustion and enhances antitumor activity of CAR-T cells through transcriptional and epigenetic modifications.

ERK1/2 Inhibitor Ulixertinib in Pan-cancer Patients with BRAF Fusions or Non-V600E/K Mutations: Results from the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol Z1L.

Inhibiting Ribosomal RNA Synthesis in C. elegans Protects Against Reductive Stress During de novo Fatty Acid Synthesis Deficiency.

Related Experiment Videos

OVCA1: emerging as a bona fide tumor suppressor

Related Concept Videos

Related Articles