Related Experiment Videos
[Open-heart surgery without donor-blood transfusion--a clinical study]
Y Umebayashi1, K Arikawa, N Chosa
1Department of Cardiovascular Surgery, Minami-kyusyu Chuoh Hospital, Kagoshima, Japan.
[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
|November 1, 1992
Summary
Open-heart surgery without donor blood transfusion showed improved postoperative outcomes. Patients had higher platelet counts and shorter intubation times, with no negative impact on renal or liver function.
Area of Science:
- Cardiovascular Surgery
- Transfusion Medicine
- Anesthesiology
Context:
- Homologous blood transfusions are common in open-heart surgery but carry risks.
- Minimizing donor blood use is a key goal in cardiac surgical procedures.
- Autologous blood conservation techniques aim to reduce transfusion requirements.
Purpose:
- To compare outcomes of open-heart surgery with and without homologous blood transfusion.
- To evaluate the efficacy of ultra-filtration and autotransfusion in reducing donor blood needs.
- To assess postoperative hematological, biochemical, and clinical parameters across different transfusion strategies.
Summary:
- Patients undergoing open-heart surgery without homologous blood transfusion (Group I) demonstrated comparable hematocrit levels to those receiving transfusions (Group II) by postoperative day seven.
- Group I exhibited significantly higher platelet counts, lower lactate dehydrogenase and bilirubin levels, and reduced blood urea nitrogen and creatinine compared to Group II.
- Shorter intra-tracheal intubation duration was observed in Group I and Group III (postoperative transfusion) compared to Group II, with no differences in catecholamine requirements.
Impact:
- This study suggests that employing techniques like ultra-filtration and autotransfusion can significantly decrease the need for homologous blood in open-heart surgery.
- Avoiding donor blood transfusions may lead to improved postoperative recovery, evidenced by better hematological parameters and reduced complications such as serum hepatitis.
- The findings support the adoption of blood conservation strategies in cardiac surgery to enhance patient safety and potentially reduce healthcare costs associated with transfusion-related issues.