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Related Experiment Videos

Flow studies in canine artery bifurcations using a numerical simulation method.

X Y Xu1, M W Collins, C J Jones

  • 1Thermo-Fluids Engineering Research Centre, City University, London, U.K.

Journal of Biomechanical Engineering
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

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This study numerically simulated canine femoral artery blood flow, finding that non-Newtonian blood properties had minimal impact on overall flow patterns. Rigid vessel walls were assumed, with future work addressing wall distensibility for quantitative comparisons.

Area of Science:

  • Biomedical Engineering
  • Fluid Dynamics
  • Computational Science

Background:

  • Understanding blood flow dynamics in arterial bifurcations is crucial for diagnosing and treating cardiovascular diseases.
  • Canine femoral artery models provide a relevant physiological system for studying hemodynamics.

Purpose of the Study:

  • To numerically predict three-dimensional blood flow through canine femoral artery bifurcation models.
  • To investigate the influence of Newtonian versus non-Newtonian blood properties on flow patterns.
  • To establish a basis for future studies incorporating arterial wall distensibility.

Main Methods:

  • Solving time-dependent, three-dimensional Navier-Stokes equations using a finite volume approach on a finite element mesh.
  • Utilizing the ASTEC code with the SIMPLE velocity-pressure algorithm.

Related Experiment Videos

  • Comparing numerical predictions with in vivo measurements.

    • Main Results:

    • Predicted velocity profiles showed good qualitative agreement with experimental in vivo measurements.
    • Non-Newtonian blood properties exhibited minimal differences in overall velocity profiles compared to Newtonian models.
    • Rigid vessel walls were assumed, representing the primary approximation in the model.

    Conclusions:

    • Non-Newtonian blood characteristics may not significantly alter general flow patterns in femoral bifurcations.
    • Local flow phenomena might be influenced by non-Newtonian effects, warranting further investigation.
    • Future research will incorporate wall distensibility for more accurate, quantitative experimental comparisons.