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Related Experiment Videos

Intrauterine death in multiple gestation.

S Liu1, K Benirschke, A L Scioscia

  • 1Department of Pathology, University of California, San Diego.

Acta Geneticae Medicae Et Gemellologiae
|January 1, 1992
PubMed
Summary
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Intrauterine fetal death in multiple gestations risks surviving infants

Area of Science:

  • Perinatology
  • Neonatology
  • Obstetrics

Background:

  • Intrauterine fetal death (IUFD) in multiple gestations poses risks to surviving infants.
  • Monochorionic placentation and velamentous cord insertions are associated with adverse outcomes.

Purpose of the Study:

  • To review cases of intrauterine fetal death in multiple gestations.
  • To analyze risks and outcomes for surviving infants.

Main Methods:

  • Retrospective review of 38 twin and 3 triplet gestations with at least one intrauterine fetal death.
  • Analysis of obstetrical history, placental pathology, autopsy findings, and neonatal history.

Main Results:

  • 34% incidence of preterm delivery, decreasing to 18% if cotwin death occurred before 20 weeks.

Related Experiment Videos

  • 72% monochorionic placentation; 79% of neurologically damaged survivors had this.
  • Neurologically damaged infants had later cotwin death and earlier delivery.
  • Conclusions:

    • Neurological damage in survivors is linked to monochorionic placentation and timing of cotwin death.
    • Causes may include exsanguination or disseminated intravascular coagulation.
    • The incidence of IUFD and neurological damage in multiple gestations may be underestimated.