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Related Experiment Videos

A psychophysical task to quantify smoking cessation-induced irritability: the reactive irritability scale (RIS).

J B Acri1, N E Grunberg

  • 1Department of Medical Psychology, Uniformed Services University of the Health Sciences, Bethesda, MD 20814.

Addictive Behaviors
|November 1, 1992
PubMed
Summary

A new psychophysical scale effectively quantifies reactive irritability during drug withdrawal. This reactive irritability scale (RIS) shows promise for assessing nicotine withdrawal symptoms where self-reports fail.

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Area of Science:

  • Psychology
  • Psychophysics
  • Neuroscience

Background:

  • Irritability is a common symptom of drug withdrawal.
  • Existing self-report measures may not accurately capture withdrawal-induced irritability.
  • A more objective measure is needed to assess this symptom.

Purpose of the Study:

  • To develop and validate a psychophysical rating scale to quantify reactive irritability.
  • To assess the utility of this scale in measuring irritability during nicotine withdrawal.

Main Methods:

  • Developed a reactive irritability scale (RIS) using magnitude estimation and environmental sound probes.
  • Tested the RIS for reliability (test/re-test) and validity.
  • Administered the RIS to abstaining smokers, non-abstaining smokers, and non-smokers.

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Main Results:

  • The RIS demonstrated good test/re-test reliability and content validity.
  • The RIS significantly differentiated abstaining smokers from non-smokers and non-abstaining smokers.
  • Self-report measures failed to distinguish between the smoker groups.

Conclusions:

  • The reactive irritability scale (RIS) offers a valid and reliable method for quantifying irritability as an index of drug withdrawal.
  • The RIS measures a different aspect of irritability (reactivity) than self-report questionnaires.
  • The RIS is recommended for studying nicotine and other drug withdrawal.