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Neutrophilic intracellular acidosis induced by conventional, lactate-containing peritoneal dialysis solutions
1Department of Medicine, School of Medicine, University of California, Irvine.
The International Journal of Artificial Organs
|November 1, 1992
Abstract:
Exposure of human neutrophils to a conventional, acidic, lactate-containing peritoneal dialysis solution (PDS) resulted in the development of a prompt and substantial intracellular acidosis. It is possible that this intracellular acidosis contributes to cellular dysfunction.