Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Problems in performing a double-blind multicenter study using a hypnotic in private practice.

W Fischer1, W Haase, E Rüther

  • 1Rhône-Poulenc Rorer GmbH, Cologne, Germany.

International Journal of Clinical Pharmacology, Therapy, and Toxicology
|November 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: Assessment of Psychosocial Functioning in a Large Cohort of Patients with Schizophrenia.

The Psychiatric quarterly·2022
Same author

Assessment of Psychosocial Functioning in a Large Cohort of Patients with Schizophrenia.

The Psychiatric quarterly·2020
Same author

Correlation of CSF- and MRI-Biomarkers and Progression of Cognitive Decline in an Open Label MCI Trial.

The journal of prevention of Alzheimer's disease·2018
Same author

Structural brain changes are associated with response of negative symptoms to prefrontal repetitive transcranial magnetic stimulation in patients with schizophrenia.

Molecular psychiatry·2016
Same author

Nutritional Effects on Central Serotonergic Activity: A Hypothesis on the Unconscious Self-manipulation of Mood by Food Intake and Dietary Selection.

Nutritional neuroscience·2016
Same author

[Not Available].

MMW Fortschritte der Medizin·2016
Same journal

Distribution of lidocaine and digoxin in heart tissues and aorta following intrapericardial administration.

International journal of clinical pharmacology, therapy, and toxicology·1993
Same journal

Population pharmacokinetic analysis of new aminoglycosides, astromicin and isepamicin, and evaluation of Bayesian prediction method for approximation of individual clearance of drug.

International journal of clinical pharmacology, therapy, and toxicology·1993
Same journal

Comparison of the pharmacokinetics of 1,2-dimethyl-3-hydroxypyrid-4-one (L1) in healthy volunteers, with and without co-administration of ferrous sulfate, to thalassemia patients.

International journal of clinical pharmacology, therapy, and toxicology·1993
Same journal

The effects of cimetidine, ranitidine and famotidine on the single-dose pharmacokinetics of naproxen and its metabolites in humans.

International journal of clinical pharmacology, therapy, and toxicology·1993
Same journal

Is there a relationship between cytarabine pharmacokinetics and keratitis?--A case report.

International journal of clinical pharmacology, therapy, and toxicology·1993
Same journal

Effect of DL-sodium lactate infusion on excretion of purine bases and oxypurinol.

International journal of clinical pharmacology, therapy, and toxicology·1993
See all related articles

The immediate data transfer and entry system (ITES) enhances data quality in multicentre studies. Non-benzodiazepine Z significantly improves sleep quality and daytime well-being compared to placebo and other benzodiazepines.

Area of Science:

  • Pharmacology
  • Clinical Research Methodology

Background:

  • Multicentre studies in private practice often face data quality challenges.
  • Assessing the efficacy of hypnotics on sleep and well-being requires reliable data collection.

Purpose of the Study:

  • To evaluate the effectiveness of the immediate data transfer and entry system (ITES) for improving data quality in multicentre studies.
  • To compare the efficacy of non-benzodiazepine Z against placebo and benzodiazepines F and T regarding sleep quality and daytime well-being.

Main Methods:

  • Implementation of the immediate data transfer and entry system (ITES) in private practice settings.
  • A comparative study assessing sleep quality and daytime well-being using non-benzodiazepine Z, benzodiazepines F and T, and placebo.

Main Results:

Related Experiment Videos

  • The ITES procedure demonstrated suitability for enhancing data quality in multicentre studies conducted in private practice.
  • Non-benzodiazepine Z showed significant superiority over placebo and slight superiority over benzodiazepines F and T in improving sleep quality and daytime well-being.
  • Patients treated with non-benzodiazepine Z reported better daytime well-being following hypnotic use for sleep induction.

Conclusions:

  • The immediate data transfer and entry system (ITES) can achieve clinical practice quality standards in private practice settings.
  • Non-benzodiazepine Z offers a favorable profile for improving both sleep induction and subsequent daytime functioning.