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Mental disorders in Parkinson's disease.

W Danielczyk1

  • 1Ludwig Boltzmann Institute for Geriatric Research, Vienna, Austria.

Journal of Neural Transmission. Supplementum
|January 1, 1992
PubMed
Summary

Psychiatric complications like depression and psychosis are common in Parkinson's disease (PD). Effective management of depression in PD patients is crucial and often requires antidepressant medication.

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Area of Science:

  • Neurology
  • Geriatrics
  • Psychiatry

Background:

  • Parkinson's disease (PD) is frequently associated with various psychiatric complications.
  • Depression, cognitive impairments, pharmacotoxic psychosis, and dementia are predominant mental disorders in PD patients.

Purpose of the Study:

  • To analyze the causes of psychiatric complications in Parkinson's disease.
  • To differentiate between PD and depression syndrome and explore their co-occurrence.
  • To investigate the relationship between antiparkinsonian medication and psychiatric disturbances.

Main Methods:

  • Analysis of psychiatric complications in patients with Parkinson's disease.
  • Long-term monitoring for differentiation between PD and depression syndrome.
  • Assessment of antidepressant treatment efficacy in PD patients.

Main Results:

  • Depression is a frequent comorbidity in elderly PD patients, often requiring antidepressant treatment.
  • Pharmacotoxic psychoses occur in 30-60% of advanced PD cases, suggesting a link with antiparkinsonian medication.
  • Dementia in PD typically arises from co-existing cerebral pathologies like SDAT and MID.

Conclusions:

  • Major depression in PD is treatable with antidepressants and independent of parkinsonian disability.
  • Antiparkinsonian drugs may contribute to psychiatric complications, particularly psychosis in advanced stages.
  • Dementia in PD is usually a result of additional neurological conditions.

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