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Hydroxymethylthiobutanoic acid spares methionine from catabolism in the chick
1Laboratoire de Physiologie Métabolique et Nutrition, Université Pierre-et-Marie-Curie, Paris, France.
Annals of Nutrition & Metabolism
|January 1, 1992
Abstract:
Two groups of chicks were fed, until they were 3 weeks old, diets supplemented with either DL-methionine (MET) or DL-2-hydroxy-4-methylthiobutanoic acid (HMB). Oxidation to CO2 and uric catabolism of intraperitoneally injected L-[1-14C]MET and DL-[1-14C]HMB were studied comparatively for 8 h. HMB supplementation spares available MET from both oxidative and uric catabolism.