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[Skin culture--keratinocytes]
G Henckel von Donnersmarck1, A Konstantinow, W Mühlbauer
1Abteilung für Plastische, Klinikum München-Bogenhausen KMB.
Langenbecks Archiv Fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft Fur Chirurgie. Kongress
|January 1, 1992
Summary
Since 1987, cultured epidermal grafts have been used for deep burns. A simple cryopreservation method for keratinocytes enables a routine supply of cultured skin grafts and allogenic epidermis.
Area of Science:
- Regenerative Medicine
- Tissue Engineering
- Dermatology
Context:
- Established in 1987, the use of cultivated epidermal grafts for deep second- and third-degree burns and donor sites.
- Development of a simple cryopreservation method for cultured human epidermal keratinocytes.
- Establishment of a skin bank in 1980 for cryopreserved allogenic cultured epidermis.
Purpose:
- To present the indications, operative management, and results of using cultivated epidermal grafts.
- To highlight the routine provision of cultured epidermografts to the intensive care unit.
- To showcase the successful implementation of a skin bank for allogenic cultured epidermis.
Summary:
- Cultivated epidermal grafts have been utilized for treating deep burns since 1987.
- A cryopreservation technique for keratinocytes has been developed, facilitating a consistent supply of grafts.
- A skin bank provides cryopreserved allogenic cultured epidermis, supporting clinical applications.
Impact:
- Routine availability of cultured epidermografts for burn treatment.
- Advancement in cryopreservation techniques for epidermal cells.
- Established infrastructure for allogenic cultured epidermis banking and utilization.