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Updated: Aug 9, 2026

Short-Duration Hypothermia Induction in Rats using Models for Studies examining Clinical Relevance and Mechanisms
Published on: March 3, 2021
Body temperature and metabolic rate during natural hypothermia in endotherms
1Department of Biology, Philipps Universität, Marburg, Federal Republic of Germany.
Abstract:
During daily torpor and hibernation metabolic rate is reduced to a fraction of the euthermic metabolic rate. This reduction is commonly explained by temperature effects on biochemical reactions, as described by Q10 effects or Arrhenius plots. This study shows that the degree of metabolic suppression during hypothermia can alternatively be explained by active downregulation of metabolic rate and thermoregulatory control of heat production. Heat regulation is fully adequate to predict changes in metabolic rate, and Q10 effects are not required to explain the reduction of energy requirements during hibernation and torpor.
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