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Pediatric laryngeal granular cell tumor
S F Conley1, M M Milbrath, D J Beste
1Department of Otolaryngology and Human Communication, Medical College of Wisconsin, Milwaukee.
Insights
Granular cell tumors of the larynx are rare in children, with subglottic involvement being more common in pediatric cases than adult ones. This study details two pediatric cases, highlighting the tumor
Area of Science:
- Pediatric Otolaryngology
- Head and Neck Pathology
Background:
- Granular cell tumor (GCT) is a rare neoplasm of neural crest origin.
- Laryngeal GCTs are uncommon, with limited pediatric case reports.
Observation:
- Two pediatric cases of laryngeal GCT are presented.
- An 8-year-old boy with a 7-year history of hoarseness due to an anterior subglottic GCT.
- An 11-year-old boy with a 1-year history of hoarseness due to a left true vocal cord GCT.
Findings:
- Pediatric laryngeal GCTs exhibit a higher predilection for subglottic involvement compared to adults.
- Subglottic GCT occurred in half of the reported pediatric cases.
- Hoarseness was the primary presenting symptom in both pediatric patients.
Implications:
- Increased awareness of laryngeal GCT in children is warranted, particularly for subglottic presentations.
- Early diagnosis and management are crucial for pediatric patients with laryngeal GCT.
- Further research into the unique characteristics and behavior of pediatric laryngeal GCT is needed.
Abstract:
Granular cell tumor of the larynx is an uncommon, benign tumor which has rarely been described in the pediatric population. Fewer than 10 cases in children under the age of 10 years have been reported. This paper describes two pediatric patients: An eight-year-old boy with a seven-year history of hoarseness due to an anterior subglottic tumor, and an 11-year-old boy with a one-year history of hoarseness due to a left true vocal cord tumor. Subglottic involvement by laryngeal granular cell tumor is rare in adults, but has been seen in half of the reported cases in the pediatric population. The clinical course of granular cell tumor and its pathology are reviewed.