Related Experiment Video

Updated: Aug 18, 2026

Membrane Potentials, Synaptic Responses, Neuronal Circuitry, Neuromodulation and Muscle Histology Using the Crayfish: Student Laboratory Exercises
16:16

Membrane Potentials, Synaptic Responses, Neuronal Circuitry, Neuromodulation and Muscle Histology Using the Crayfish: Student Laboratory Exercises

Published on: January 18, 2011

[Strychnine-induced changes of the membrane and postsynaptic potentials in neocortical neurons]

V E Lopantsev

    Neirofiziologiia = Neurophysiology
    |January 1, 1992
    PubMed

    More Related Videos

    Preparation of Acute Brain Slices Using an Optimized N-Methyl-D-glucamine Protective Recovery Method10:53

    Preparation of Acute Brain Slices Using an Optimized N-Methyl-D-glucamine Protective Recovery Method

    Published on: February 26, 2018

    Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity11:56

    Slice Patch Clamp Technique for Analyzing Learning-Induced Plasticity

    Published on: November 11, 2017

    Related Concept Videos

    Excitatory and Inhibitory Effects of Neurotransmitters01:29

    Excitatory and Inhibitory Effects of Neurotransmitters

    When an action potential reaches the presynaptic axon terminal, it releases neurotransmitters from the neuron into the synaptic cleft at a chemical synapse. The released neurotransmitter can be excitatory or inhibitory. The critical criteria commonly used to determine whether a molecule is a neurotransmitter at a chemical synapse are the molecule's presence in the presynaptic neuron. Second, its release is in response to strong presynaptic depolarization. And lastly, the presence of specific...
    Chemical Synapses01:26

    Chemical Synapses

    Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
    Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...
    Neurochemical Transmission: Sites of Drug Action01:26

    Neurochemical Transmission: Sites of Drug Action

    Neurochemical transmission, the conduction of electrical impulses between neurons mediated by neurotransmitters, plays a vital role in various physiological processes. Autonomic drugs exert their effects by modulating neurotransmission within the autonomic nervous system. For instance, drugs such as hemicholinium block the precursor uptake necessary for synthesizing acetylcholine, an essential autonomic neurotransmitter. Following synthesis, neurotransmitters are stored in vesicles. Metyrosine...
    Depolarizing Blockers: Mechanism of Action01:28

    Depolarizing Blockers: Mechanism of Action

    Depolarizing blockers act on skeletal muscle fibers' membranes and induce their depolarization. Most depolarizing blockers have two quaternary N+ atoms that bind the nicotinic acetylcholine receptors and cause neuromuscular blockade within minutes.
    Succinylcholine is the most commonly used depolarizing blocker. Chemically, it constitutes two molecules of acetylcholine joined together by an acetate methyl group. They act on the receptors in the same way as acetylcholine. Because succinylcholine...
    Depolarizing Blockers: Pharmocokinetics01:19

    Depolarizing Blockers: Pharmocokinetics

    Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...
    Chemical Synapses01:26

    Chemical Synapses

    Chemical synapses are specialized sites between two neurons or between a neuron and a non-neuronal cell like a muscle, glandular or sensory cell.
    Because chemical synapses depend on the release of neurotransmitter molecules from synaptic vesicles to pass on their signal, there is an approximately one millisecond delay between when the axon potential reaches the presynaptic terminal and when the neurotransmitter leads to opening of postsynaptic ion channels. Additionally, this signaling is...