[Multiple meningiomas in different compartments of the cerebrospinal axis]

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A Visual Description of the Dissection of the Cerebral Surface Vasculature and Associated Meninges and the Choroid Plexus from Rat Brain
12:31

A Visual Description of the Dissection of the Cerebral Surface Vasculature and Associated Meninges and the Choroid Plexus from Rat Brain

Published on: November 14, 2012

M Zumkeller1, V Seifert, H Dietz

  • 1Neurochirurgische Klinik, Medizinische Hochschule Hannover.

Der Nervenarzt
|December 1, 1992
PubMed

Insights

Multiple meningiomas in different neuroaxial compartments are exceptionally rare. This study details four unique cases of meningiomas occurring in distinct brain and spinal regions at different times.

Area of Science:

  • Neurosurgery
  • Oncology
  • Neuropathology

Background:

  • Multiple meningiomas, typically confined to one neuroaxial compartment, are uncommon.
  • Meningiomas occurring in separate supratentorial and spinal compartments are exceedingly rare, with few documented instances.

Observation:

  • This report presents four distinct cases of patients with multiple meningiomas.
  • Each case featured two meningiomas located in different neuroaxial compartments (supratentorial and spinal).
  • Tumor development occurred asynchronously and in separate locations within these compartments.

Findings:

  • Radiological and operative findings for each case are detailed.
  • The study explores potential etiologies including cerebrospinal fluid or hematogenous dissemination.
  • Multifocal origin and genetic predisposition are considered as possible causes.

Implications:

  • Highlights the rare occurrence of multiple meningiomas across different neuroaxial compartments.
  • Contributes to understanding the potential pathways of meningioma spread or multifocal development.
  • Informs clinical suspicion and diagnostic approaches for rare presentations of meningioma.

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