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[Lymphocytic molecules implicated in rosette phenomenon. Differential effect of antilymphocyte serum on T (CD2+E2+)
M Ticchioni1, G Bernard-Pomier, E Cassuto-Viguier
1Laboratoire d'Immunologie, Hôpital de l'Archet, Nice.
Therapie
|July 1, 1992
Abstract:
The molecule E2 is present on T lymphocytes and thymocytes and is implicated in rosette phenomenon most probably via interaction with CD2. The discrepancy observed between rosette levels and lymphocyte phenotypes in the follow-up of kidney-transplanted patients treated with antilymphocyte globulins (ALG), methylprednisolone and azathioprine leaded us to study the effect of ALG on E2 molecule.