[Cold agglutinin syndrome after rubella infection]

Cold agglutinins are antibodies against erytrocyte membrane antigens, and are produced primarily or secondarily. We report on the case of a 5 year old girl who developed cold agglutinin disease 3 days after an attack of German measles. Following exposure to cold, appeared blue-red cutaneous manifestations of the fingers, hands cheeks and nose. The clinical manifestations cleared up without any specific therapy. The occurrence of cold agglutinins after German measles is rare. The case report is discussed within the context of reports in the literature.