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Acute uric acid nephropathy in pregnancy
E Alexopoulos1, P Tampakoudis, H Bili
1First Department of Obstetrics and Gynecology, Aristotelian University of Thessaloniki, Hippokration General Hospital, Greece.
Obstetrics and Gynecology
|September 1, 1992
Summary
Acute uric acid nephropathy is a rare cause of kidney failure in pregnant women. Prompt treatment with hydration, urine alkalinization, and mannitol can effectively restore renal function.
Area of Science:
- Nephrology
- Obstetrics
- Toxicology
Background:
- Uric acid clearance typically increases during pregnancy.
- Uric acid nephropathy is an uncommon cause of acute kidney injury in pregnant individuals.
Observation:
- A 38-year-old pregnant woman at 30 weeks' gestation presented with acute renal failure.
- Diagnosis was confirmed by severe hyperuricemia and a high uric acid-creatinine ratio.
Findings:
- Treatment involved forced diuresis, urine alkalinization, and mannitol infusion.
- The patient experienced rapid and full recovery of kidney function.
Implications:
- Acute uric acid nephropathy during pregnancy is treatable with standard medical interventions.
- Successful management allows for a healthy pregnancy outcome.