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Coronary artery embolism with special reference to invasive procedures as the source
C Yutani1, M Imakita, H Ueda-Ishibashi
1Department of Pathology, National Cardiovascular Center, Suita, Japan.
Insights
Coronary artery embolism, often linked to invasive cardiovascular procedures, is more common than previously believed. This condition, particularly atheromatous emboli, can lead to myocardial infarction and death, requiring clinical vigilance.
Area of Science:
- Cardiology
- Pathology
Background:
- Coronary artery embolism (CAE) has been sporadically reported following invasive cardiovascular procedures since 1978.
- The incidence of CAE in relation to the increased application of these procedures remains unclear.
Purpose of the Study:
- To investigate the incidence and causes of coronary artery embolism.
- To determine if CAE has increased with the wider use of invasive cardiac interventions.
Main Methods:
- Retrospective review of autopsy cases with suspected acute myocardial infarction at the National Cardiovascular Center from 1977 to 1990.
- Analysis of 28 confirmed cases of coronary artery emboli.
Main Results:
- Eighteen cases (10% of myocardial infarction autopsies) confirmed coronary artery emboli.
- Invasive procedures were the cause in 14 patients (50%), including 8 with atheromatous emboli.
- Half of the resulting myocardial infarcts were hemorrhagic; 11 patients died directly from the embolism.
Conclusions:
- Coronary artery embolism is not as rare as previously thought and may be increasing with advancements in invasive cardiovascular procedures.
- Clinicians in cardiovascular fields must maintain awareness of CAE as a potential complication.
Abstract:
Since 1978, there have been sporadic reports of coronary artery embolism caused by cardiac catheterization, percutaneous transluminal coronary angioplasty, and other invasive procedures. To determine whether coronary artery embolism has increased with the wider application of such procedures, we searched for patients with coronary artery emboli among the autopsy cases with suspected acute myocardial infarction at the National Cardiovascular Center from 1977 to 1990. Of the 28 patients with emboli, 10% of the total autopsy cases of myocardial infarction was confirmed in 18. Infarction was diagnosed clinically in only six of these patients and directly caused the death of 11 of the 18 patients. In contrast to previous reports, where a minority of coronary emboli were caused by instrumentation, 14/28 patients in our series had coronary embolism due to invasive procedures, including eight patients with atheromatous emboli. half of the myocardial infarcts caused by embolism were hemorrhagic. Thus, coronary emboli are not so rare as once thought, and they may increase further with the progress of invasive diagnostic and surgical interventions. The possibility of coronary embolism thus needs to be kept in mind by all clinicians in the cardiovascular fields.