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Updated: Aug 26, 2026

Pulsed Wave Doppler Assessment of Diastolic Dysfunction in the ZSF-1 Rat Model of Pulmonary Hypertension Due to Left Heart Disease
Published on: May 22, 2026
[Does diastolic heart failure exist?]
José Fernando Guadalajara Boo1
1Instituto Nacional de Cardiología Ignacio Chávez INCICH, Juan Badiano No. 1 Col. Sección XVI, Tlalpan 14080 México, D.F. Guadalajara@cardiologia.org.mx
Insights
The term "diastolic heart failure" is inaccurate and confusing. This review advocates for using "diastolic dysfunction" to clearly define heart conditions and improve treatment.
Area of Science:
- Cardiology
- Physiology
- Pathophysiology
Context:
- Historical evolution of heart failure concepts.
- Current understanding of cardiac physiology and pathophysiology.
- Clinical confusion surrounding diastolic dysfunction terminology.
Purpose:
- To review the concepts of systolic and diastolic heart function.
- To discuss the inappropriateness and confusion generated by the term 'diastolic heart failure'.
- To emphasize the need for clear distinction between heart failure and diastolic dysfunction.
Summary:
- The term 'diastolic heart failure' is imprecise and creates confusion in clinical practice, treatment, and research.
- Diastolic dysfunction is a distinct clinical entity with its own pathophysiology, prognosis, and treatment needs.
- Accurate terminology is crucial for improving clinical guidelines, research design, and patient care.
Impact:
- Promotes clearer diagnostic criteria for heart conditions.
- Aids in developing more targeted and effective treatment strategies.
- Enhances consistency and accuracy in clinical research and reporting.
Abstract:
This paper reviews the concepts of systolic function, diastolic function, heart failure, diastolic dysfunction, and diastolic heart failure. We refer to the historic evolution of the concept of heart failure and the origin of the term diastolic heart failure. Based on the current concepts of the physiology of the heart and its pathophysiology, we discuss the inappropriateness of the term and to the confusion it has generated in clinical practice, treatment, and prognosis, as well as in numerous research papers (of which some examples are given) when terming as "heart failure" the diastolic dysfunction and using both terms indistinctively. We conclude that an increasing need has arisen, ever more imperative, to identify clearly the concepts of heart failure and diastolic dysfunction, emphasizing on their differences to recognize them as distinct clinical entities with their own personality and, hence, having different prognosis and treatment. This would be of great help to achieve more accuracy in the clinical guidelines, standards, and consensus, especially regarding treatment. Besides it would be useful to avoid, inconsistencies in the design of research, which appear in some of the publications just by the lack of a clear meaning of the terms. Finally, at present we have the necessary elements to conclude that the terms "diastolic heart failure" and "cardiac failure with preserved systolic function" are inexact, poorly gauged, and far away from the actual problem they try to define. Therefore, they should be substituted by the concept of Diastolic Dysfunction, which defines clearly the pathophysiology of the functional alteration, without having to state that "the heart is failing".
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