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Physical and Chemical Factors in the Home and Workplace before and during Pregnancy
Elisabeth Robert-Gnansia1, Anne-Marie Saillenfait
1Institut Européen des Génomutations, Lyon, France. elisabeth.robert@ieg.assoc.fr
Objective:
To present and discuss current knowledge about the relationship between physical and chemical factors in the home and workplace and adverse reproductive outcomes in the offspring.
Design And Methods:
Critical review of the scientific literature, focusing mostly on epidemiological research. Reviews and original papers involving human occupational and home exposures to physical and chemical agents and their relation to adverse reproductive outcomes were screened and commented upon.
Results:
Only a small proportion of the several thousands of occupational/home exposures have been adequately assessed for reproductive or developmental toxicity. This is reflected in the difficulties of identifying causal associations in humans and in the lack of data.
Conclusion:
According to present knowledge, very few authors confirmed that reproductive hazards exist in environmental agents, but increased surveillance of occupational exposures in relation to workers' reproductive health is highly desirable in order to assess moderate risks.
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