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Left ventricular long-axis function is reduced in patients with rheumatic mitral stenosis

Necla Ozer1, Ilknur Can, Enver Atalar

  • 1Department of Cardiology, Hacettepe University Faculty of Medicine, Ankara, Turkey. neclaozer@hotmail.com

Echocardiography (Mount Kisco, N.Y.)
|February 14, 2004
PubMed

Insights

Patients with mitral stenosis show impaired left ventricular long-axis function, detected by M-mode and tissue Doppler echocardiography, even with normal global systolic function. This highlights subtle cardiac changes in mitral stenosis.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiac Physiology

Background:

  • Left ventricular long-axis function is a key indicator of systolic function.
  • Previous studies established M-mode and tissue Doppler echocardiography as valuable tools for assessing this function.
  • However, its specific evaluation in patients with mitral stenosis, particularly those with preserved global function, remained underexplored.

Purpose of the Study:

  • To investigate and quantify left ventricular long-axis function in patients with pure mitral stenosis.
  • To compare these measurements with those of healthy controls.
  • To determine if mitral stenosis affects long-axis function independently of global systolic function.

Main Methods:

  • Echocardiographic assessment of 52 patients with pure mitral stenosis and 22 healthy controls.
  • Evaluation of left ventricular long-axis function using M-mode echocardiography (annular motion) and tissue Doppler echocardiography (annular systolic velocity).
  • Global systolic function was assessed by left ventricular fractional shortening.

Main Results:

  • No significant difference in global systolic function (left ventricular fractional shortening) was observed between patients and controls.
  • Patients with mitral stenosis exhibited significantly reduced M-mode derived systolic motion of both septal and lateral mitral annulus compared to controls.
  • Tissue Doppler-derived systolic velocities of the septal and lateral mitral annulus were also significantly lower in patients with mitral stenosis than in controls.
  • A significant correlation was found between septal annular motion, annular velocity, and left atrial ejection fraction.

Conclusions:

  • Patients with pure mitral stenosis demonstrate significantly impaired left ventricular long-axis function.
  • This impairment is detectable by both M-mode and tissue Doppler echocardiography.
  • These findings suggest that long-axis dysfunction is present in mitral stenosis, even when global systolic function appears normal.

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