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Is otitis media with effusion a biofilm infection?
N Fergie1, R Bayston, J P Pearson
1Department of Otolaryngology and Head and Neck Surgery, Queen's Medical Centre, Nottingham, UK. neil.fergie@virgin.net
Clinical Otolaryngology and Allied Sciences
|February 14, 2004
Abstract:
Recent attention has focused on the possibility that otitis media with effusion (OME) may represent a chronic infective state such as those evidenced in conditions secondary to biofilms or small colony variants. This review discusses the evidence suggesting that this may indeed be the case and explains why this may prove to be important in the future management of this condition by discussing recent advances in understanding these bacterial phenotypic variants.