Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bupropion for Blau syndrome.

Eric Lewin Altschuler1, Richard E Kast

  • 1Department of Psychiatry, University of Vermont, 2 Church Street, Burlington, VT 05401, USA. eric.altschuler@mssm.edu

Medical Hypotheses
|February 14, 2004
PubMed
Summary

Blau syndrome (BS), a genetic disorder causing granulomas and arthritis, may be treatable with bupropion. This medication has shown effectiveness in treating a similar condition, Crohn

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Polypharmacy, polypharmacology, and polypharmacotherapy: clarifying definitions and complementary roles in cancer treatment - a narrative review.

Expert review of anticancer therapy·2026
Same author

Pharmacodynamic profile of Hexadimethrine Bromide-induced eosinophilia - Roles of pro-eosinophilic mediators.

European journal of pharmacology·2026
Same author

A New Adjuvant Treatment for Glioblastoma Using Aprepitant, Vortioxetine, Roflumilast and Olanzapine: The AVRO Regimen.

International journal of molecular sciences·2025
Same author

UBC4: A Repurposed Drug Regimen for Adjunctive Use During Bladder Cancer Treatment.

Biomedicines·2025
Same author

Potential Benefits of Adding Alendronate, Celecoxib, Itraconazole, Ramelteon, and Simvastatin to Endometrial Cancer Treatment: The EC5 Regimen.

Current issues in molecular biology·2025
Same author

Noninvasive Ultra Low Intensity Light Photodynamic Treatment of Glioblastoma with Drug Augmentation: LoGlo PDT Regimen.

Brain sciences·2025

Area of Science:

  • Genetics and immunology
  • Pharmacology

Background:

  • Blau syndrome (BS) is an autosomal dominant disorder.
  • BS is characterized by granulomas and arthritis.
  • CARD15 gene mutations are linked to BS and Crohn's disease (CD).

Purpose of the Study:

  • To explore potential treatments for Blau syndrome.
  • To investigate the efficacy of bupropion for BS treatment.

Main Methods:

  • Literature review of BS and CD.
  • Analysis of CARD15 gene mutations in BS and CD.
  • Evaluation of bupropion's efficacy in Crohn's disease.

Main Results:

  • CARD15 mutations are implicated in Blau syndrome.
  • Bupropion has demonstrated effectiveness in treating Crohn's disease.
  • No specific treatments are currently established for Blau syndrome.

Conclusions:

  • Bupropion is a potential therapeutic candidate for Blau syndrome.
  • Further research is warranted to confirm bupropion's efficacy in BS.

Related Experiment Videos