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Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
Published on: September 14, 2014
Specific interaction of feline immunodeficiency virus surface glycoprotein with human DC-SIGN
Aymeric de Parseval1, Stephen V Su, John H Elder
1Department of Molecular Biology, The Scripps Research Institute, La Jolla, California 92037, USA.
Journal of Virology
|February 14, 2004
Abstract:
DC-SIGN, a specific C-type lectin expressed on dendritic cells, binds and transmits multiple strains of primate immunodeficiency viruses to susceptible cells. Here, we report that human DC-SIGN also captures feline immunodeficiency virus via high-affinity (1 nM), Ca(2+)-dependent, D-mannose-inhibited binding to the major envelope glycoprotein, gp95.
