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Frequency of hypertension in chronic Chagas' disease: retrospective clinical study
Cristina Brandt Friedrich Martin Gurgel1, Armando Miguel Junior, Clayde Regina Mendes
1Faculdade de Medicina, Pontifícia Universidade Católica de Campinas, SP, Brazil. cbfmgurgel@ig.com.br
Insights
Hypertension occurs in Chagas disease patients at rates similar to the general population. Cardiologic findings in these patients do not significantly differ from other Chagas disease patients.
Area of Science:
- Cardiology
- Infectious Diseases
- Public Health
Background:
- Chagas disease, caused by Trypanosoma cruzi, can lead to cardiac complications.
- Hypertension is a common comorbidity in cardiovascular diseases.
Purpose of the Study:
- To determine the prevalence of hypertension in patients with chronic Chagas disease.
- To analyze the clinical behavior and cardiologic findings associated with hypertension in this population.
Main Methods:
- Retrospective study of 225 patients with chronic Chagas disease and hypertension.
- Data collected from 1984 to 2000, including clinical, electrocardiographic, and radiological assessments.
Main Results:
- Hypertension prevalence was 33.3% among the studied Chagasic patients.
- Cardiac enlargement was observed in 44.9% of cases; conduction disorders were also common.
- The undetermined form of Chagas disease was most prevalent, followed by conduction disorders.
Conclusions:
- The frequency of hypertension in Chagasic patients is comparable to the general population.
- Clinical and cardiologic profiles of hypertensive Chagasic patients do not markedly differ from non-hypertensive Chagasic patients.
Objective:
To assess the frequency of hypertension in chagasic patients, as well as its clinical behavior and cardiologic findings.
Methods:
We carried out a retrospective study with 225 patients with chronic Chagas' disease and hypertension (104 males), mean age of 55.1 11.8. These patients were being followed up in the outpatient care clinics from 1984 to 2000. The study assessed the clinical, electrocardiographic, and radiological viewpoints.
Results:
Of the 225 hypertensive patients (prevalence = 33.3%), 78 (34.7%) had mild hypertension, 108 (48%) had moderate hypertension, and 39 (17.3%) had severe hypertension. The association of left anterosuperior divisional block and right bundle-branch block occurred in 39 cases (17.3%), and enlargement of the cardiac area on radiological examination occurred in 93 (44.9%) of the 207 cases studied. The undetermined form of Chagas' disease was the most prevalent, 30.2% of the cases, followed by the form associated with conduction disorders in 27.1%, and the isolated form of conduction disorders in 21.3%.
Conclusion:
Chagasic patients had a frequency of hypertension similar to that of the general population, and the clinical profile of the hypertensive chagasic patients seemed not to differ a lot from that of the chagasic patients.
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