[Study on the anti-oxidation function of nucleic acids]

To study the anti-oxidation function of nucleic acids both in animal experiment and in human. (1) Anti-oxidation test in aged rats: Using 32 aged female SD rats, divided into 3 dose groups and 1 control group. Each group had 8 rats. Mixing deferent doses nucleic acid capsule with drinking water and fad doses groups for 50 days. The control group was given only drinking water. On 51st day, measuring the serum malondialdehyde (MDA), superoxide dismutase (SOD) and glutathione peroxidase(GSH-Px). (2) Eating observation test in aged people: Choosing 120 volunteers aged 50-65 who came from some community in Shanghai, divided into eating observation group and control group. Each group had 60 people. Each people ate 6 capsules per day for 60 days. The control group used same capsule except nucleic acids. On 61st day, measuring the serum MDA, SOD and GSH-Px.

Anti-oxidation test in aged rats showed that the concentrations of serum MDA in all dose groups are lower than that of the control (P < 0.01). The concentrations of serum SOD in low and middle dose groups are higher than those of control (P < 0.01, P < 0.05). The concentrations of serum GSH-Px in all dose groups are higher than those of control (P < 0.01). Eating observation test in aged people showed that the concentration of serum SOD in eating observation group is higher than that of the control (P < 0.05), the concentrations of serum MDA and GSH-Px have no significant compared with the control. The appetite, vigorous and energy of eating observation group are significantly improved compared with the control (P < 0.05).

The nucleic acid capsule has anti-oxidation function in aged female SD rats. The nucleic acids alone could promote SOD and improve the appetite, vigorous and energy of human body.