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Quantitative determination of rofecoxib in pharmaceutical preparations
1Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Marmara, Istanbul, Turkey.
Die Pharmazie
|February 18, 2004
Abstract:
Rofecoxib was assayed by UV spectrophotometry and HPLC, the concentration ranges were 2-30 microg x ml(-1) and 5-50 microg x ml(-1), respectively. The results, obtained by the two methods in pharmaceutical preparations were compared of each other. There were no significant differences between the mean values and the precisions.