Related Experiment Video
Updated: Aug 26, 2026

Establishment of a Murine Pulp Exposure Model with a Novel Mouth-Gag for Pulpitis Research
Published on: October 27, 2023
Dentinal hypersensitivity: review of aetiology, differential diagnosis, prevalence, and mechanism
M Al-Sabbagh1, S Andreana, S G Ciancio
1Department of Periodontology and Endodontology, School of Dental Medicine, SUNY at Buffalo, NY 14214, USA.
Abstract:
Dentinal hypersensitivity is a painful response to a non-noxious stimulus applied to exposed dentine in the oral environment. Dentine exposure results from a combination of two or more aetiological factors that lead to loss of enamel and/or loss of cementum. The hydrodynamic theory is the most accepted theory that explains the excitement of pulpal nerve fibres by a stimulus applied to the exposed dentine. Dentinal hypersensitivity had been reported to affect middle age people most often with no gender differences and has been shown to be influenced by tooth location.
Related Concept Videos
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Hypersensitivity Reactions: Delayed Hypersensitivity Reactions
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin and...
Analgesia and Pain Management
Local Anesthetics: Differential Sensitivity of Nerve Fibers
Hypersensitivities
Types of Hypersensitivities
Hypersensitivity reactions are categorized into four types: Type 1, Type 2, Type 3, and Type 4. Each type has a distinct mechanism...