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Modifying Baculovirus Expression Vectors to Produce Secreted Plant Proteins in Insect Cells
Published on: August 20, 2018
Expression and secretion of functional recombinant scu-PA:AV in insect cell using signal peptides
Yuhui Huang1, Ruiyang Tian, Wei Hu
1Shanghai Research Center of Biotechnology, Chinese Academy of Sciences, Shanghai 200233, PR China.
Protein and Peptide Letters
|February 18, 2004
Abstract:
A fusion protein (scu-PA:AV) was expressed in the baculovirus expression system and secreted from Sf9 cells lead by signal peptides, 2mel and 3egt. The scu-PA:AV displays both the urokinase activity and membrane binding activity of its parental components. Our work indicated that it is possible to be developed as a thrombus-targeting drug.
