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Related Experiment Videos

Birthweight discordance in multiple pregnancy.

Isaac Blickstein1, Robin B Kalish

  • 1Dept. of Obstetrics and Gynecology, Kaplan Medical Center, Rehovot, and the Hadassah-Hebrew University School of Medicine, Jerusalem, Israel. blick@netvision.net.il

Twin Research : the Official Journal of the International Society for Twin Studies
|February 18, 2004
PubMed
Summary

Discordant growth in multiple pregnancies is common and varies in severity. Higher discordance levels increase risks, with smaller fetuses in severely discordant pairs facing the greatest danger.

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Area of Science:

  • Perinatology
  • Maternal-Fetal Medicine
  • Neonatology

Background:

  • Discordant growth in multiple pregnancies is a significant clinical concern.
  • Understanding patterns and implications of discordant growth is crucial for optimizing outcomes.

Purpose of the Study:

  • To review key aspects of discordant growth in multiple pregnancies.
  • To elucidate the relationship between discordance levels, gestational age, and adverse outcomes.

Main Methods:

  • Review of existing literature on discordant growth in multiple gestations.
  • Analysis of accepted observations and clinical implications.

Main Results:

  • Discordant growth is observed in approximately 25% of twins, with higher rates in triplets.

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  • Increased discordance levels correlate with greater risk of adverse outcomes.
  • Severely discordant fetuses, particularly the smaller ones, face disproportionately high neonatal mortality risk.

    • Conclusions:

    • Discordant growth patterns vary and are not always indicative of growth restriction.
    • Clinical implications of discordance differ based on gestational age.
    • Management strategies should consider discordance severity and gestational age for improved neonatal outcomes.