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Published on: December 4, 2013
Mechanisms of verbal memory impairment in four neurodevelopmental disorders
Sharon Nichols1, Wendy Jones, Mary J Roman
1Department of Neurosciences, University of California, 9500 Gilman Drive, MC-0935, San Diego, CA 92093-0935, USA. slnichols@ucsd.edu
Abstract:
Profiles of verbal learning and memory performance were compared for typically developing children and for four developmental disorders characterized by different patterns of language functioning: specific language impairment, early focal brain damage, Williams Syndrome, and Down Syndrome. A list-learning task was used that allowed a detailed examination of the process of verbal learning, recall, and recognition (California Verbal Learning Test--Children's Version). Distinct patterns of performance characterized the four disorders. These patterns were consistent with the language deficits typically seen in the disorders, with the exception of a dissociation seen in Williams Syndrome.
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