Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Morphologic changes in breast biopsies after duct endoscopy.

F Tresserra1, R Fábregas, J Torrent

  • 1Department of Pathology, Institut Universitari Dexeus, Paseo de la Bonanova 69, 08017 Barcelona, Spain. 25865ftc@comb.es

Breast (Edinburgh, Scotland)
|February 18, 2004
PubMed
Summary

Duct endoscopy, a breast imaging technique, causes minor tissue changes like epithelial detachment and stromal disaggregation. These changes are distinct from malignancy and useful for interpreting biopsy results.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Barium ion sensing with IPG K<sup>+</sup> molecular probes.

The Analyst·2025
Same author

In-plane dielectric constant and conductivity of confined water.

Nature·2025
Same author

Effect of fish oil in Iberian sow diets on fatty acid, oxylipins and immune traits of colostrum and milk, and suckling piglets' growth performance.

Animal : an international journal of animal bioscience·2025
Same author

Six weeks of a concurrent training therapy improves endothelial function and arterial stiffness in hypertensive adults with minimum non-responders.

Hipertension y riesgo vascular·2024
Same author

Comparison of sediment bioavailable methods to assess the potential risk of metal(loid)s for river ecosystems.

Ecotoxicology and environmental safety·2024
Same author

The impact of loneliness and social isolation on the benefits of an exercise program with hospitalised older adults.

The journal of nutrition, health & aging·2024

Area of Science:

  • Pathology
  • Surgical Pathology
  • Breast Imaging

Background:

  • Duct endoscopy offers direct visualization of the breast ductal system.
  • The procedure involves low-pressure irrigation with saline solution.
  • Potential morphological alterations in breast tissue require investigation.

Purpose of the Study:

  • To assess morphological changes in breast tissue induced by duct endoscopy.
  • To differentiate these changes from pathological conditions like malignancy.

Main Methods:

  • Comparison of 26 breast biopsies from duct endoscopy patients with 26 controls.
  • Histopathological analysis of breast tissue specimens.
  • Evaluation of epithelial and stromal changes.

Related Experiment Videos

Main Results:

  • Duct endoscopy specimens showed significantly higher rates of epithelial detachment (73%), epithelial loss (35%), periductal clefts (77%), stromal disaggregation (46%), and epithelial cell displacement (27%).
  • Control group showed minimal epithelial detachment (4%), periductal clefts (15%), and stromal disaggregation (15%).
  • Epithelial loss and displacement were absent in controls.

Conclusions:

  • Low-pressure fluid perfusion during duct endoscopy induces distinct morphological changes in breast tissue.
  • These changes are distinguishable from malignancy.
  • The observed changes are likely artifacts resulting from duct rupture during the procedure.