Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calciphylaxis causing necrotizing mastitis: a case report.

P A Kay1, W Sanchez, J F Rose

  • 1Department of Laboratory Medicine and Pathology, Rochester, MN 55905, USA.

Breast (Edinburgh, Scotland)
|February 18, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Precision Measurement of Neutrino Oscillation Parameters with 10 Years of Data from the NOvA Experiment.

Physical review letters·2026
Same author

Widespread slow growth of acquisitive tree species.

Nature·2025
Same author

Silicosis initially presenting with empyema.

Occupational medicine (Oxford, England)·2024
Same author

Authors' Response to Correspondence Re Ethnic Differences in Radiotherapy Outcomes in a Majority South Asian Leicester Community.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same author

Predicting CO<sub>2</sub> production of lactating dairy cows from animal, dietary, and production traits using an international dataset.

Journal of dairy science·2024
Same author

Oral Cavity Cancers: Ethnic Differences in Radiotherapy Outcomes in a Majority South Asian Leicester Community.

Clinical oncology (Royal College of Radiologists (Great Britain))·2024
Same journal

Antibody-drug conjugates beyond HER2: Translating evidence into practice for HR+ HER2-negative and triple-negative metastatic breast cancer.

Breast (Edinburgh, Scotland)·2026
Same journal

Comment on comparator design in regional versus general anesthesia for ambulatory breast-conserving surgery.

Breast (Edinburgh, Scotland)·2026
Same journal

HER2DX genomic assay in HER2-positive early breast cancer treated with trastuzumab and pertuzumab: A correlative analysis from a real-world cohort.

Breast (Edinburgh, Scotland)·2026
Same journal

Patient satisfaction following Goldilocks mastectomy in non-obese women: A pilot study.

Breast (Edinburgh, Scotland)·2026
Same journal

Concerns about anesthetic standardization and interpretability in the comparison of regional anesthesia with dexmedetomidine versus general anesthesia.

Breast (Edinburgh, Scotland)·2026
Same journal

Translating CLEOPATRA into routine practice: National treatment patterns and survival for patients with HER2-positive metastatic breast cancer.

Breast (Edinburgh, Scotland)·2026
See all related articles

Calciphylaxis, a rare condition often linked to kidney disease, can cause severe skin necrosis. This case highlights calciphylaxis leading to necrotizing mastitis after a breast biopsy for microcalcifications.

Area of Science:

  • Medical Case Study
  • Pathology
  • Dermatology

Background:

  • Calciphylaxis is a rare, severe condition characterized by vascular calcification and skin necrosis.
  • It is most frequently associated with end-stage renal disease (ESRD) and secondary hyperparathyroidism.
  • The condition can manifest in various tissues, leading to significant morbidity.

Purpose of the Study:

  • To report an unusual case of calciphylaxis presenting as necrotizing mastitis.
  • To emphasize the importance of considering calciphylaxis in the differential diagnosis of breast lesions, even in the absence of typical risk factors.
  • To highlight the diagnostic and management challenges associated with extraskeletal calcification.

Main Methods:

  • Case report detailing a patient who developed necrotizing mastitis.

Related Experiment Videos

  • Review of clinical presentation, diagnostic workup, and histopathological findings.
  • Discussion of the patient's medical history, including a recent breast biopsy for microcalcifications.

    • Main Results:

    • The patient presented with painful, necrotic breast lesions following a routine breast biopsy.
    • Histopathology confirmed vascular calcification and necrosis consistent with calciphylaxis.
    • The condition was identified as a complication of the initial biopsy procedure in the context of underlying risk factors.

    Conclusions:

    • Calciphylaxis can present atypically, including as necrotizing mastitis, even after minimally invasive procedures like breast biopsy.
    • Early recognition and diagnosis are crucial for appropriate management and to prevent further complications.
    • This case underscores the need for heightened clinical suspicion for calciphylaxis in patients with unexplained skin necrosis, particularly those with risk factors such as chronic kidney disease or hyperparathyroidism.