Related Experiment Video
Updated: Jul 26, 2026

12:18
Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Bacterial endocarditis associated with a skin-tunnelled catheter
1Department of Clinical Oncology, Western General Hospital NHS Trust, Crewe Road, Edinburgh EH4 2XU, UK.
Breast (Edinburgh, Scotland)
|February 18, 2004
Summary
Skin-tunnelled catheters provide long-term central venous access but carry risks. This case highlights a rare complication: bacterial endocarditis following catheter removal due to associated venous thrombosis.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Cardiology
Background:
- Skin-tunnelled catheters are essential for long-term central venous access in cancer patients.
- These lines facilitate chemotherapy, fluid/blood product administration, and nutritional support.
- Potential complications include infection, thrombosis, and dislodgement.
Purpose of the Study:
- To report a rare case of bacterial endocarditis.
- To investigate the link between central venous catheter use and subsequent cardiac infection.
- To emphasize the importance of recognizing line-associated thrombosis complications.
Main Methods:
- Case report detailing a patient's clinical course.
- Review of potential complications associated with skin-tunnelled catheters.
- Investigation of line-associated brachiocephalic venous thrombosis.
Main Results:
- The patient developed bacterial endocarditis affecting the pulmonary valve.
- This occurred shortly after the removal of a skin-tunnelled catheter.
- The endocarditis was linked to pre-existing line-associated brachiocephalic venous thrombosis.
Conclusions:
- Line-associated venous thrombosis is a significant complication of central venous catheters.
- Bacterial endocarditis can arise as a consequence of catheter-related thrombosis.
- Vigilance for and management of venous thrombosis are crucial in patients with central venous access devices.
Related Concept Videos
Skin Diseases and Disorders
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
Endocarditis I: Introduction
Introduction:Endocarditis is the infection of the endocardium, the inner lining of the heart and its valves. When the heart muscle is involved, the condition is termed myocarditis, while an infection of the outer lining is called pericarditis. Infective endocarditis (IE) primarily affects the endocardium, where pathogens adhere to the valves or lining, forming vegetation that can lead to severe complications. Infective endocarditis occurs when microorganisms, usually bacteria from other body...
Endocarditis II: Clinical Features of Infective Endocarditis
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
Endocarditis III: Medical Management
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
Endocarditis IV: Nursing Management
Infective endocarditis (IE) is a chronic infection of the heart's endocardium, primarily affecting the heart valves. A detailed nursing assessment for a patient with IE involves collecting subjective and objective data to ensure an accurate diagnosis and timely intervention.Subjective DataThe nurse gathers information about the patient's symptoms and complaints during the subjective assessment. Patients with infective endocarditis often report non-specific symptoms that can mimic other...
Staphylococcal Skin Infections
Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

