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Updated: Aug 26, 2026
Magnetic and Thermal-sensitive Poly(N-isopropylacrylamide)-based Microgels for Magnetically Triggered Controlled Release
Published on: July 4, 2017
Preparation and characterization of polybutylcyanoacrylate magnetic nanoparticles
Fei Ren1, Jian-hai Chen, Yao-dong Jiang
1Department of Pharmacy, Nanfang Hospital, First Military Medical University, Guangzhou 510515, China. renfeisky@163.net
Objective:
To Prepare and characterize polybutylcyanoacrylate (PBCA) magnetic nanoparticles.
Methods:
The suspension of PBCA magnetic nanoparticles was prepared by emulsion polymerization method. The particle size, size distribution, polydispersity and other parameters were determined by photon correlation spectroscopy and transmission electron microscopy, and the iron content in the nanoparticles by ultraviolet spectroscopy.
Results:
The data of the particle size and size distribution of aqueous decanoic acid stabilized Fe3O4 magnetic fluids were acquired, and the influences of concentrations of butylcyanoacrylate (BCA) and Dextran-70 on the particle size and size distribution of PBCA magnetic nanoparticles were characterized.
Conclusion:
We have for the first time successfully prepared stable suspension of PBCA magnetic nanoparticles by emulsion polymerization method at pH 6.3-6.4 in aqueous medium.
