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[A clinical study of doxycycline slow-release gel on periodontitis chemotherapy]
Hong-lai Jin1, Chun-zheng Hu, Jian-guo Chen
1Department of Periodontics, Ninth People's Hospital, School of Stomatology, Shanghai Second Medical University, Shanghai 20001, China.
Objective:
To observe the effect of Doxycycline slow-release on periodontitis therapy.
Methods:
30 patients with chronic periodontitis were chosen and divided into 2 groups randomly,these cases were given Doxycycline slow-release and Zinciodati Comp solution. PLI,GI,SBI,PD,AL,MD and clinical symptoms were observed before and after taking drug.
Results:
The indose of PLI,GI,SBI,PD,AL,MD were decreased significantly after the use of Doxycycline slow-release gel (P<0.05),the effects of the Doxycycline was better than Zinciodati Comp solution (P<0.01), no adverse drug side effects were found during trial.
Conclusion:
The use of Doxycycline slow-release gel is one of the safe and effective chemotherapy on periodontitis.
