Related Experiment Video
Updated: Aug 19, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
Published on: November 29, 2015
[Leber's optic neuropathy presenting as an alcohol- and tobacco-related optic neuropathy]
N Leveziel1, N Guépratte, D A Lebuisson
1Service d'Ophtalmologie, Hôpital Foch, Suresnes.
Abstract:
The authors report a case of a 70-year-old man presenting a recent unilateral decrease in visual acuity, appearing in a context of alcohol and tobacco intoxication. Diagnosis of Leber's optic neuropathy was evoked after elimination of other causes of a visual acuity decrease such as giant cell arteritis and compressive or inflammatory optic neuropathy. The authors emphasize that Leber's optic neuropathy must be evoked in a recent decrease in visual acuity, even if it appears in an unusual context.
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