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[Diabetes and tuberculosis--bad companions]
1Department of Medicine, Metabolism & Endocrinology, Juntendo University School of Medicine, 2-1-1, Hongo, Bunkyo-ku, Tokyo 113-8421, Japan. kawamori@med.juntendo.ac.jp
Abstract:
Diabetes and tuberculosis are bad companions each other. In this clinical review article on diabetes, the pathophysiology of diabetes is documented from the viewpoint of both insulin secretory dynamics and insulin action on various target organs. The mechanisms why atherosclerosis is accelerated in diabetes is also mentioned. Nowadays, there are many modalities to correct the deranged glucose fluxes, thus it is not difficult to maintain near-normal glycemic excursions in diabetic patients. Strict glycemic regulation is obligatory if the patient with tuberculosis has diabetes.
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