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Updated: Aug 26, 2026

Automated HPLC Separation Using LC-Mate: An Integrated Repetitive Autosampler and Fraction Collector for Microscale Purification
Published on: February 27, 2026
Part II. Chromatography using ultra-stable metal oxide-based stationary phases for HPLC
1Department of Water Treatment Technology, Faculty of Chemistry, A. Mickiewicz University, Drzymały 24, 60-613 Poznań, Poland. jaceknaw@amu.edu.pl
Abstract:
In this part of the review authors discuss methods used for modification of metal oxide surfaces. On the basis of literature data it is shown, that silanization of the surfaces do not form stable supports for chromatography. On the other hand, the success of polymer modified surfaces such as polybutadiene (PBD) and polystyrene (PS) is emphasized. Permanent modification of metal oxide surfaces with Lewis bases is also widely discussed. Chromatographic properties of polymer modified surfaces of zirconia are discussed in details. The perspectives of carbon-coated metal oxide surfaces in HPLC and high temperature separations are described.
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