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A High-throughput Cell Microarray Platform for Correlative Analysis of Cell Differentiation and Traction Forces
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Design considerations for efficient and effective microarray studies

M Kathleen Kerr1

  • 1Department of Biostatistics, University of Washington, Box 357232, Seattle, Washington, USA. katiek@u.washington.edu

Biometrics
|February 19, 2004
PubMed

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Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...